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[7] [9] Usage depends on eGFR thresholds, and patients should receive sick-day guidance (temporarily stopping during acute illness) Thiazolidinediones (e.g., pioglitazone): May improve insulin sensitivity but carry risks of weight gain, fluid retention, and fractures [11] [17] Sulfonylureas (e.g., gliclazide): Effective but associated with hypoglycaemia and weight gain Basal insulin : For patients with significant hyperglycaemia, especially if symptomatic or with very high HbA1c (75 mmol/mol or 9%), insulin therapy may be necessary DPP-4 inhibitors (e.g., sitagliptin) are an alternative class of medication when GLP-1 receptor agonists are unsuitable
Some patients experience mild symptoms for 6 to 8 weeks, particularly if they advance their dose quickly
& Boehncke, W.-H
Never inject fasted unless you're very experienced
The study also included a sample size of 20, but it featured a treatment duration of 3 months
