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Rosenstock, et al
doi: 10.1038/s41467-025-56344-5 241 LawrenceDSZilfouJTSmithCD
[2] [6] Report new or worsening symptoms promptly, including severe abdominal pain (potential pancreatitis), visual changes, chest pain, leg swelling or pain (potential thrombosis), unexplained vaginal bleeding, or persistent gastrointestinal symptoms
Clinical data from the SURMOUNT trials showed that approximately 25 to 30 percent of weight lost on tirzepatide comes from lean mass rather than fat
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