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Seeley, consults for GLP-1 drugmakers
Diarrhoea and constipation represent opposite ends of the digestive spectrum, yet both are commonly reported
In a typical medication-only model: Patients may see rapid initial weight loss But 5070% stop taking the drug within a year (AJMC Study) And those who stop regain much of the lost weight within months (JAMA) Why
Given the significance of S -palmitoylation in cancer, the DHHCs and protein depalmitoylases are promising targets for cancer therapy
J.FrancisD.OliverN.et al (2018)
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