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These approaches can minimise gastrointestinal side effects and support overall wellbeing during treatment
domestica ) exhibits significant DPP-IV inhibitory activity in vitro ( Although direct evidence connecting phytochemicals to incretin-mediated neuroprotection in PD is still emerging, it is biologically plausible that phytochemical-driven DPP-IV inhibition or incretin stimulation could enhance neuronal energy metabolism, mitochondrial function, and anti-inflammatory signaling, thereby protecting dopaminergic neurons
The LEADER trial with liraglutide and the SUSTAIN-6 trial with semaglutide demonstrated cardiovascular benefits that may be partially mediated through anti-inflammatory mechanisms
For infants, low maternal vitamin D status has been associated with an increased risk of preterm birth (birth before 37 weeks of gestation) and low birth weight (a newborn weighing less than 2,500 grams) (115-118)
B12 is water-soluble, and its generally safe even at very high doses
