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In that case, clinicians will typically consider safer or better-suited alternatives and set up more intensive monitoring if semaglutide is used

When there is a suspicion of symptomatic B12 deficiency it is important to measure the B12 serum determination (in addition to excluding other diseases, such as thyroid diseases and Lyme), even if anaemia has not been diagnosed

Therefore, novel therapeutic strategies for this disease must be developed

GLP-1 acts by inhibiting key cytokines such as TNF- , IL-17 , IL-23 and IL-22 , molecules that are strongly implicated in the skin inflammation seen in diseases such as psoriasis and hidradenitis suppurativa