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And and thats what were trying to do
HLC cultures were incubated with conventional probe substrates for CYP3A4 (6 M midazolam), CYP2C9 (10 M diclofenac), and CYP2D6 (10 M dextromethorphan) for 2 hours
The report described a 13-year-old boy with a heterozygous LOF MC4R variant (p.Glu61Lys), accompanied by autism spectrum disorder and trypanophobia, who developed obesity at approximately 6 months of age
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