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While myricetin's complex with DPP-4 was mostly stabilized by hydrogen bonds and van der Waals forces, electrostatic forces may play a significant role in maintaining the complexes of the other four flavonoids with DPP-4
All rats used in this study were kept at a humidity of 50%60% and a temperature of 25C, with food and water being freely accessible
References StatPearls (NCBI Bookshelf) Farzam K, Patel P
The results is also consistent with reports with other GLP-1 agonists [20], which exert organ-protective effects through GSK3-dependent pathways in non-cardiac tissues
PLoS ONE 6 , e14504 (2011)
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