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Despite widespread marketing of vitamin B12 pills and injections as weight loss aids, there is no robust clinical evidence to support this claim in individuals who are not deficient
Oral Protocols: Daily oral doses of 1, 5, 10, 20, and 30 mg were evaluated over 12 weeks
Early and smaller studies suggested effects on fat metabolism and body fat distribution, but larger obesity trials did not show a robust, clinically meaningful weight loss outcome on their own
This uptake depends on a protein called intrinsic factor (IF), which captures B12 in the small intestine, absorbing it in the final stretch of your small intestine (the ileum)
This can make it harder for them to absorb and use vitamin B12
