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The NRF2, thioredoxin, and glutathione system in tumorigenesis and anticancer therapies

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Under stress conditions, activated microglia release inflammatory factors that drive neuroinflammation, whereas in a tissue repair state, they promote neuroprotection ( 42 significantly increased TNF- mRNA expression, this effect was suppressed by choline deficiency and Lico E treatment

The other activates three metabolic receptors simultaneously, suppressing appetite, improving insulin sensitivity, and ramping up energy expenditure