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A critical component was the establishment of an in vitro co-culture system using 12-well plates and 0.4 m pore size transwell inserts
PLoS ONE 6(3):e17899 Sun H, Yang T, Li Q et al (2012) Dexamethasone and vitamin B(12) synergistically promote peripheral nerve regeneration in rats by upregulating the expression of brain-derived neurotrophic factor
B12 injections can be mildly painful for some however most patients can tolerate the discomfort well
These include: Mild nausea or digestive discomfort (more common with oral forms) Dizziness or lightheadedness Injection site irritation, redness, or swelling Possible changes in appetite These side effects typically go away on their own and do not pose long-term risks
Long-term safety data is lacking, so potential unknown side effects may exist.
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