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Benefits should be balanced with risks such as hormonal disruption, side effects, lack of long-term safety data, and the risk of unregulated products, which require medical oversight and monitoring

By affecting all these cellular functions already impaired in aging individuals it could explain why older, comorbid patients have the most severe outcomes with COVID-19 (312) and stimulate the use of GSH and Nrf2 enhancers as well as develop new therapies to protect mitochondria

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Notably, the researchers did not observe any change in melatonin levels in young monkeys who were given the same treatment [7]

This is challenging when tirzepatide suppresses appetite, so dense protein sources become important