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Urban, N
As fibrotic scarring accumulates, nephron function declines irreversibly, underscoring the importance of targeting fibrosis as a central pathway in developing therapeutics for CKD
Longer half-life : Effects last longer than oral or IV options
These bonds and the three-dimensional structure of the peptide can be disrupted by several environmental factors: Heat: Accelerates chemical degradation reactions including hydrolysis and oxidation Moisture: Triggers hydrolysis of peptide bonds
Lancet 365 , 15611569 (2005)
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