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Li J, et al
In addition, treatment effects estimated using MMRM analyses are typically larger than those seen with MI analyses since the MMRM estimates the treatment effect while participants are adhering to the investigational drug, whereas MI-based estimates (reflecting the intent-to-treat approach) are irrespective of adherence
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In BAT, both lean and obese mice showed increased 3-AR expression following treatment, again paralleling reductions in BAT weight
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