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Some reports in literature and reviews list risks like possible skin-peeling disorders (rare)
PMID 10759684
However, long-term co-cultures with neural stem cells have proven difficult due to the relative immaturity of astrocytes (Krencik et al., 2011)
however, further validation and optimization will be necessary to differentiate between BBB breakdown associated with AD versus other neuroinflammatory disorders
Epigenetics in endothelial dysfunction The importance of epigenetics in developing endothelial dysfunction and CVD is becoming more evident
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