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SURPASS-2 showed tirzepatide was superior to semaglutide 1mg for both A1C reduction (2.09% vs 1.86%) and weight loss (12.4% vs 6.2%) at the 15mg dose, establishing the clinical relevance of dual-agonism over selective GLP-1 agonism
Both units are used, but mcg is more common for B12 doses, mainly for smaller amounts
For most healthy patients, yes
The in vitro metabolic data established the half-life of AOD9604 in human serum and identified the primary metabolic pathways responsible for its clearance
B12 shots start to work much faster than vitamins taken orally
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