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This extreme expansion is both its superpower and its risk
While tirzepatide does not directly affect B12 absorption like metformin, reduced intake of animal productscommon during appetite suppressionmay lead to inadequate B12 levels
Patients on those medications should only receive B-Complex injections with close monitoring (and dosage adjustments of the anticonvulsant if needed)
Mean weight loss was 14.9% at 68 weeks with semaglutide 2.4 mg vs 2.4% with placebo
3.2 TM6SF2 TM6SF2 gene, located on chromosome 19p13.3, encodes a protein involved in hepatic lipid metabolism and has been strongly implicated in MASLD pathogenesis (113)
