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Future research should focus on patient-specific responses, genetic factors, and long-term outcomes to refine treatment approaches
GLP-1 Success Story GLP-1 agonists (also called GLP-1RAs), and related drugs like dual agonists of gastric inhibitory polypeptide (GIP)/GLP-1, have revolutionized obesity treatment by demonstrating significant and sustained weight loss in clinical trials and real-world use
Conversely, M2-polarized macrophages secrete cytokines such as IL-10 and TGF-, which activate anti-ferroptotic signaling cascades within tumor cells
GSH is a reducing substrate of GPX4 activity, which is essential for preventing and inhibiting ferroptosis
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