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It helps to know how these differ so you can respond appropriately

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Doses start very low (0.25 mg weekly for semaglutide) and titrate up slowly

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Although this patient showed improvements in HbA1c and a decrease in body mass index ([BMI] from 205% of the 95th percentile, BMI 41 kg/m 2 to 202%, BMI 39 kg/m 2 ) with all prescribed medications (e.g., metformin, topiramate), adherence challenges prompted introduction of semaglutide to simplify her regimen

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Three catalysts should have moved the number by then: two-PBM access confirmed by mid-May, Medicare Bridge access starting July 1, and full-scale TV advertising in Q3

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