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4), including the following: Nanoparticle-based systems : These systems employ nanocarriers, including polymeric nanoparticles, solid lipid nanoparticles (SLNs) and inorganic nanoparticles, to encapsulate lignans and enhance their therapeutic efficacy through targeted and controlled release mechanisms

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Beyond the phagocytic respiratory burst, G6PD acts more generally as a key regulator of cellular redox homeostasis and provides substrate for NADPH oxidase by generating NADPH, thus exerting an innate immune modulatory role in these capacities