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In a research context, the main limitations are the gap between animal and human data, stability sensitivity requiring proper storage, and the risk of compromised results if purity is not independently verified

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A 2022 systematic review in Growth Hormone & IGF Research identified 47 clinical trials involving Tesamorelin versus 23 for Sermorelin reflecting the significantly higher clinical investment in Tesamorelins metabolic applications

The current trend leans towards a leaner, more defined look rather than the bulky appearance associated with steroid use

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