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It is worth noting that: Phase 2 trials typically involve smaller sample sizes, limiting the ability to detect adverse events occurring in fewer than 15% of participants
This is not surprising given that melatonins role as a hormone is not to induce sleep but to signal to the body that it is nighttime
Finally, a triagonist was synthesized to include GLP-1, Gcg, and GIP agonism (Finan et al., 2015)
For permanent solutions, a combination of treatments may be recommended
CONFLICT OF INTEREST The author of this work declares that she has no conflicts of interest
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