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ERAD helps mitigate this burden by degrading these proteins, thereby preventing their aggregation and the subsequent activation of detrimental pathways, such as chronic ER stress, autophagy dysfunction, and apoptotic signaling

Currently, there are clinical studies using AAV vectors to transfect sarcoplasmic/endoplasmic reticulum Ca (2+)-ATPase (SERCA2a) to treat heart failure [255, 256]

Hydration, diet, sleep, and alcohol can all influence how you respond

Supplementary information Supplementary Table 1 and uncropped western blots for Extended Data Fig

Professional Consultation: Always consult with a dermatologist or healthcare professional before starting any glutathione treatment, especially injections