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Yamasaki T, Hirose H, Yamashita T et al (2017) Discovery of novel somatostatin receptor subtype 5 (SSTR5) antagonists: Pharmacological studies and design to improve pharmacokinetic profiles and human Ether-a-go-go-related gene (hERG) inhibition

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The research team opted for a method that directly compares periods when the same person took the drug with periods when they did not, minimizing errors due to individual differences

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