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Intestine-specific gene transfer experiments of pancreatic and duodenal homeobox-1 ( Pdx1 ) siRNA in 810-week-old mice reveal that posteriori suppression of Pdx1 decreases K-cell number, intestinal GIP protein and mRNA expression, and GIP secretion in response to an oral glucose tolerance test (OGTT) (Ikeguchi et al., 2018)
PCR products were purified using Hieff NGS DNA Selection Beads and the library quality was assessed using the Qubit 2.0 Fluorometer (Life Technologies)
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If a physician determines GH axis intervention is clinically appropriate, those approved options represent a much higher evidence standard
