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When glutathione levels are depleted - as they consistently are in Hashimoto's thyroiditis, Graves' disease, and hypothyroidism - the consequences cascade: oxidative thyroid damage, protein modification, autoantigen formation, immune activation, and progressive thyroid destruction
& Wooten, M
Additionally, Mounjaro , one of the newer diabetes drugs, which was approved in May 2022 and has a unique dual mechanism of action (it activates the GLP-1 hormone as well as another hormone called the glucose-dependent insulinotropic polypeptide or GIP, both helping to improve blood sugar) may be even more effective than semaglutide in reducing weight
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The fact that this redox imbalance occurs as a consequence of GSH depletion may explain why several clinical trials have provided no evidence of significant cataract prevention arising from the administration of high dosages of ascorbic acid [13]
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