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On the material engineering front, the increasing structural sophistication of lysosome-targeted nanomaterials presents a major translational hurdle

Sulfonylureas should be tapered by 50% at the 4 mg step and discontinued before the 12 mg step unless persistent hyperglycemia (fasting glucose consistently above 200 mg/dL) justifies continuation [13]

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Giustarini D, Dalle-Donne I, Colombo R, Milzani A, Rossi R

[20] The University of Washington's "The 4-Digit Diagnostic Code", which ranks the four key features of FASD on a Likert scale of one to four and yields 256 descriptive codes that can be categorized into 22 distinct clinical categories, ranging from FAS to no findings