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They are not necessarily better or worse, just different tools for different aspects of the problem

What seems to matter most: What your appetite was like before you started How long you were on treatment Your dose Whether you built healthy habits you can maintain without the medication Should you taper off a GLP-1 or stop cold turkey

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Also, patients on tirzepatide were less likely to progress to a worse UACR stage (HR 0.43, 95% CI 0.270.71) and more likely to regress to a less severe UACR stage (HR 1.97, 95% CI 1.512.57) compared to insulin glargine [49]