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This stage is generally considered the threshold for a CKD diagnosis, and it falls into two subcategories: 3a and 3b

Weekly injections instead of daily

To mitigate these concerns, we included several proxy indicators in our propensity score matching, such as socioeconomic determinants (captured through ICD codes related to employment status, housing circumstances, and social environment), lifestyle counseling codes, and medication profiles that often correlate with health behaviors

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Metalloporphyrins contain Mn or Fe metals coordinated by four donor nitrogens in a square planar arrangement and have been reported to scavenge superoxide radicals (O 2 ) (Pasternack and Skowronek 1979), hydrogen peroxide (H 2 O 2 ), peroxynitrite (ONOO ) and hydroperoxides (LOOH) (Day et al