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citalopram, fluoxetine, sertraline (anxiety and depression) Drugs metabolised by CYP450 2D6: Codeine (opioid painkiller) Inducers CYP450 2C19: Rifampicin (TB) Carbamazepine (epilepsy, trigeminal neuralgia) Inhibitors CYP450 2C19: Lansoprazole, omeprazole (reflex and heartburn) Drugs metabolised by CYP450 2C19: Warfarin (anticoagulant) Diazepam (sedative, anxiolytic) Phenytoin (epilepsy) Inducers CYP450 2C9: Rifampicin (TB) Carbamazepine (epilepsy, trigeminal neuralgia) Inhibitors CYP450 2C9: Miconazole (antifungal) Fluconazole (antifungal) Drugs metabolised by CYP450 2C9: Warfarin (anticoagulant) Non-steroidal anti-inflammatories Clopidogrel (antiplatelet) Genetical variations Genetic variations can lead to altered CYP450 polymorphisms and so altered metabolism of drugs
doi: 10.1016/j.rmed.2022.107035 88 YangYWangYGuoLGaoWTangT-LYanM
Trends Endocrinol
BPC-157 has been associated with modulation of dopaminergic and serotonergic signaling pathways, both of which are essential for emotional balance, motivation, and cognitive processing
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