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Targeting TfR is particularly well-studied: for example, NPs functionalized with transferrin, anti-TfR antibodies, or peptides like T7 or OX26 exhibit enhanced brain uptake due to their ability to engage the endogenous transferrin transport system [10]
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Vitamin C, vitamin E, plant polyphenol, carotenoids, and glutathione are nonenzymatic antioxidants, which act by interrupting free radicals chain reactions
Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions