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cardiometabolic risk reduction

Survodutide (BI 456906) is similar to the active ingredient tirzepatide (Mounjaro, Zepbound) in that it combines two mechanisms of action

In another broad aspect the present invention relates to an anion exchange chromatography process for purifying a peptide from a mixture comprising said peptide and related impurities, comprising the step of: separating said peptide and said related impurities of said mixture by elution in a solution consisting essentially of an organic modifier, water, optionally a salt component, and optionally a buffer, with a linear or step gradient or isocratically in salt component and/or with a linear or step pH-gradient or at a constant pH-value, wherein the pH-gradient or pH-value should be in the range where said peptide has a negative local or overall net charge different from the local or overall negative net charge of said related impurities so as to remove said related impurities

Compounded medications may vary in duration, primarily when sourced from custom pharmacies

Of the respondents, 84% said diabetes was a top health priority, while 83% cited obesity and 56% said cardiometabolic disease