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The liver, which maintains the highest concentrations of glutathione in the body (5 to 10 mM), is the primary site of this detoxification activity
The more accurate measurement of brain iron concentration is provided by quantitative susceptibility mapping (QSM), which has shown notable specificity in determining iron content in TBI lesions and neurodegenerative patterns (Koch et al., 2021
However, maintaining a nutritious diet can synergize with the treatment
The use of more specific evaluations, especially tools that target cognitive domains known to be affected more prominently and earlier in PD (e.g., executive functions) could help identify and characterize the effects of probiotics on cognition in PD