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doi:10.2337/diabetes.52.2.380 34
The compound of formula-8 which is used in the above described process is prepared by a process, comprising, a) treating compound of formula-16 with di.tert-butyl dicarbonate (DIBOC), t-butanol in presence of a base in a solvent to provide compound of formula- 17, b) reacting compound of formula- 17 with compound of formula- 19 in a solvent optionally in presence of a coupling agent and/or a base to provide compound of formula-8
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B12 is water-soluble, and excess amounts are simply excreted by the kidneys
This mainstream acceptance reflects a growing recognition of the complexity of weight management and the importance of a multifaceted approach to achieve sustainable results
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