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Description

NORSE and FIRES are defined below: Epilepsia partials continua (EPC) is defined & discussed here: NORSE NORSE definitions New-onset Refractory Status Epilepticus (NORSE) : New-onset seizure with refractory status epilepticus (i.e., refractory to two medications such as benzodiazepine plus levetiracetam)

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NICE guidelines recommend hydroxocobalamin 1 mg intramuscularly three times weekly for 2 weeks (without neurological involvement) or on alternate days until no further improvement (with neurological symptoms)

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