However, due to the unwanted side effects, such as glucose intolerance, insulin resistance, hypertension and edema, exerted by other functional domains of the intact hGH molecule limited its use as pharmacotherapy for obesity In other words, AOD9604 induces fat loss without the side effect of insulin resistance seen in many other peptides that stimulate growth hormone production/release
In LEADER, there was a higher, albeit non-significant, rate of adverse retinal events with liraglutide compared with placebo (HR 1.15, 95% CI 0.871.52
Anything that promotes new blood vessel formation is a theoretical concern in the context of a tumor's blood supply, and the responsible default is caution
Khavinson et al
Individuals diagnosed with T2DM and at high risk for cardiovascular issues were studied to determine the effects of tirzepatide on their heart health