Daver N, Garcia-Manero G, Basu S, Cortes J, Ravandi F, Jabbour E, Assi R, Brandt M, Pierce S, Gordon T, Pemmaraju N, Andreeff M , Ning J, Kornblau S, Kadia T, Flores W, Matthews J, Dinardo C, Konopleva M, Allison J, Sharma P, Kantarjian H
Immune cells are highly sensitive to oxidative stress during activation, and the intracellular glutathione pool can influence inflammatory signaling pathways and the balance between pro-oxidant and antioxidant responses
Daily use for months to years is common practice
Frolova O, Frankel AE, Korchin B, Cortes J, Kantarjian HM, Andreeff M , Konopleva M
Until results from this dedicated study are available, its unlikely that cagrilintide will move forward for approval on its own just yet