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It enhances the insulin response, suppresses glucagon secretion, promotes satiety and improves insulin sensitivity

Furthermore, studies using a peripherally administered exenatide analogue conjugated to vitamin B12, which is sterically hindered from accessing regions protected by the blood brain barrier, improves glucose control in comparable fashion to unmodified exenatide, presumably at the level of the -cell, but does not induce emesis in the house musk shrew ( Suncus murinus) or rats (78, 79)

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They also enhance the bodys antioxidant defense system by regenerating other antioxidants such as vitamin C and glutathione