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Also, histidine 96 and histidine 111 (human PrP numbering) that are located outside the octarepeat region, are also actively involved in PrP-Cu 2+ binding (Snchez-Lpez et al., 2018)

Do not use in children, pregnant women, or breastfeeding women

While alternative administration routes, such as intravenous, intramuscular, nasal, percutaneous, and transdermal delivery, have shown promise in certain conditions, these methods can be invasive and uncomfortable for patients

2023 Jul 24;14