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doi: 10.1007/s00384-014-2030-8
Multi-dose vials should be discarded 28 days after the first puncture, regardless of how much medication remains
Reported laboratory observations include activation of downstream PI3K/Akt and MAPK/ERK signaling cascades and associated effects on cell proliferation, protein-synthesis pathways, and anti-apoptotic signaling in cultured cells
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More than 1 in 8 participants were completely free from knee pain by the end of the trial
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