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GLP-1 receptor agonists, and related dual GIP/GLP-1 agonists, are injectable or oral medications that mimic hormones involved in blood sugar control and appetite
doi: 10.1136/jitc-2023-007349 211 TodenhferTSeilerRStewartCMoskalevIGaoJLadharSet al
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It is widely used for liver diseases and other conditions, like skin whitening
126 USP20 stabilizes HMG-CoA reductase (HMGCR), the rate-limiting enzyme in cholesterol biosynthesis, and its inhibition reduces lipid levels and improves insulin sensitivity in preclinical models
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