tirzepatide and semaglutide Maintenance therapy on or TrimRX | Semaglutide vs Tirzepatide:

(28) The crude incidence rates of LLA were 6.1 per 10,000 person-years for GLP-1 receptor agonists, 1.5 for SGLT-2 inhibitors, 4.6 for DPP-4 inhibitors, and 1.9 for older agents

Over 6 months (the typical initial treatment period), brand-name Wegovy costs $8,094 without insurance or $3,000 to $3,900 with the savings card

While prior literature cites a 510% defect rate among women with pregestational diabetes, this study did not report any significant pregnancy losses following the use of GLP-1RA (92)

Mouth sores, if they occur, may be multifactorial and warrant clinical assessment to exclude other causes such as viral infections, nutritional deficiencies (particularly vitamin B12, which can also be associated with metformin use in type 2 diabetes, folate, or iron), or autoimmune conditions

Amylin is a hormone that contributes to satiety, delays gastric emptying, and suppresses postprandial glucagon secretion