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10.1016/j.freeradbiomed.2007.02.009 Free Radic

[11] [15] For gastric banding patients, annual blood tests are generally recommended as a minimum once stable, covering: Serum vitamin B12 Full blood count (to detect macrocytic or megaloblastic anaemia) Serum ferritin and iron studies Vitamin D, calcium, and parathyroid hormone (PTH) Folate Thyroid function and other metabolic markers as clinically indicated The specific tests and frequency recommended may vary according to the procedure performed, individual clinical circumstances, and local protocols

Deficiency can also be caused by poor absorption

Healthcare professionals involved in peptide and molecular research

Since then, several clinical studies have shown its safe and effective use - but the pharmacuetical companies have decided not to (yet) pursue FDA-Approval (likely because each new FDA-Approval costs several million dollars to go through the process, and because there are a good deal of drugs used off-label in the way tranexamic acid is for melasma, especially when the drug has a long history of safety and efficacy, as is in this case)