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This was confirmed by the identification of phosphorylation sites on key lipogenic and glucose metabolism enzymes in liver of mice treated with cotadutide
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However, the burden of gastrointestinal side effects was confirmed in the high-dose group
It is no coincidence, then, that the share of Americans using weight-loss drugs more than doubled between early 2024 and summer 2025, from 5.8% to 12.4%
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