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The modification was developed to help enhance the half-life of the protein and allow it to obstruct the normal FOXO4 function
Oral and non-injectable GLP-1 delivery has similarly generated substantial momentum
Interestingly, gastric sleeve surgery itself increases natural GLP-1 production, which contributes to its weight loss effects
Retatrutide is currently undergoing trials and has yet to achieve approval
10.1210/endo.141.1.7263 80 SugandhF.ChandioM.RaveenaF.KumarL.KarishmaF.KhuwajaS.et al (2023)
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