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At the 10mg dose, tirzepatide achieves plasma concentrations that exceed the activation threshold for both receptors by substantial margins, roughly 10,000-fold above the EC50 for the GIP receptor and 250-fold above the EC50 for the GLP-1 receptor
HUBERMAN: Now, when we say positive effects, we have to stand back and say, well, what's the control experiment
Snack volumes are down across the board for the last two years, with a few segment exceptions (tortilla chips)
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