Concurrently, altered glucose metabolism in the orbitofrontal cortex and limbic regions reflects energy deficits and mitochondrial dysfunction, contributing to the severity of psychiatric symptoms, such as paranoia, agitation, and mood disturbances (Chang et al., 2007)
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Though this was rather surprising it was also found in another Danish study by Rasmussen and colleagues 23 that boys tend to overestimate pubertal maturation when self-assessing compared to girls which may be an explanation to the surprising finding, but also underline that the puberty data in this study should be interpretated with caution