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46 Overexpression of efflux transporters such as P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in tumors limits intracellular drug accumulation, while physical barriers such as the bloodbrain barrier constrain effective delivery to sites such as gliomas

Neuroprotection and Anticonvulsant Properties: Studies suggest DSIP stabilizes neural activity, reduces excitotoxicity, and possesses anti-convulsant properties, potentially by potentiating the action of anti-epileptic drugs in seizure models

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