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For example, in the SURMOUNT-1 trial, approximately 75% of the weight lost was fat mass and 25% was lean mass
As body weight decreases, thyroid hormone requirements may change, potentially leading to symptoms of hyperthyroidism if the levothyroxine dose remains unchanged
Generally, this ECD conformation can be acquired by rotating the ECD roughly 30 horizontally from its position in the crystal structure (Fig
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it's signaling that its regulatory architecture has shifted and homeostasis requires recalibration
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