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SCFAs, especially butyrate, modulate the immune system by activating G-protein-coupled receptors (GPCRs), particularly G-protein-coupled receptor 43 (GPR43) and G-protein-coupled receptor 109A (GPR109A) (169)
6 Formalin-induced nociceptive behavioral test Male Sprague Dawley rats (250~300 g) (n = 35) were randomly divided into the control (n = 7), 5 mg/kg morphine (n = 7) and BPC-157 groups (n = 21) to establish the inflammatory pain model and conduct the behavior test
Some patients may also experience mild temporary side effects such as: Injection site soreness Redness or swelling Headache Nausea Mild muscle cramping These effects are generally mild and resolve quickly
S.SchnepelN.HansenK.SchmickeM.Muscher-BanseA
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