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5 Iron homeostasis and immune regulation in the tumor microenvironment 5.1 Impact of macrophage polarization states on iron metabolism During early tumorigenesis, M1-type tumor-associated macrophages (TAMs) facilitate cellular iron uptake via transferrin receptor 1 (TfR1/CD71), while ferritin (FT) restricts iron efflux, resulting in iron sequestration
IPA has several subsidiaries in North America and Europe including entities such as Talem Therapeutics LLC, BioStrand BV, ImmunoPrecise Antibodies (Canada) Ltd
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